The highest snow accumulations are expected east of Lake Ontario, where some isolated areas could get up to 60 inches of lake effect snow early in the week.

An Arctic blast brought snow, frost and dangerously cold winds to the northern Plains, Midwest and Great Lakes, creating difficult travel conditions on one of the busiest travel days of the year, as millions of Americans head home from their Thanksgiving destinations.

An arctic blast of severe cold and snow is creating hazardous conditions across the Great Lakes region over the next two days, according to the US Weather Prediction Center, potentially disrupting the plans of millions traveling the roads and skies.

Lake-effect snow warnings were in effect through Tuesday night in parts of Ohio, New York and Pennsylvania while nearly 4 feet fell in upstate New York and parts of Pennsylvania and Michigan.

A lake-effect snowstorm is continuing to pound Great Lakes communities as millions brace for more frigid air this week.

An Arctic blast of cold air is expected to hit much of the U.S. into next week, sending temperatures plummeting. More than 230 million Americans are being impacted by the “dangerously cold” weather following a snowy and rainy Thanksgiving Day, according to FOX Weather.

Some parts of the country will receive heavy lake-effect snow and others will see rain or dry weather with subfreezing temperatures.