The Buffalo Bills are fresh off of their bye week heading into a Sunday Night Football matchup with the San Francisco 49ers, who are in serious danger of missin

The 49ers travel to Buffalo to take on the AFC East-leading Buffalo Bills. Check out our best bet for the game

NFL Week 13 odds, picks, predictions, TV and streaming information for Sunday Night Football game between the San Francisco 49ers and Buffalo Bills.

The Buffalo Bills sit a 9-2 through 12 weeks of the 2024 NFL campaign. At this time last season, it looked as though the sky was falling in Orchard Park.

It’s Week 13 in the NFL, and the Buffalo Bills have a chance to secure their fifth consecutive AFC East title, setting a new franchise record. For this to happen, Buffalo (9-2) first needs the Miami Dolphins (5-6) to fall to the Green Bay Packers on Thanksgiving night. Then, the Bills must defeat the San Francisco 49ers on Sunday Night Football.

The Bills aren’t going to settle for just a playoff spot. They can clinch the AFC East in Week 13. Buffalo has nine wins to the Miami Dolphins’ five, but the Bills have the head-to-head tiebreaker over the Dolphins thanks to two wins. If both teams finish 9-7, Buffalo wins the tiebreaker.

Kansas City Chiefs quarterback Patrick Mahomes has been fined more than $14,000 for pantomiming what the NFL deemed a "violent gesture" during a game last week against the Buffalo Bills.

Patrick Mahomes will probably find a new way to celebrate a big play moving forward. The Kansas City Chiefs' star quarterback was fined over $14,000 by the NFL for what was deemed a "violent gesture" during Kansas City's Week 11 loss to the Buffalo Bills.