San Francisco running back Christian McCaffrey suffered a knee injury that coach Kyle Shanahan described as “potentially” ...

It's Buffalo Bills vs San Francisco 49ers in Week 13 of the NFL season. Can Josh Allen and company outduel Christian McCaffery and Deebo Samuel?

The Bills and the San Francisco 49ers went head-to-head in freezing conditions Sunday, with Bills fans and staff digging out ...

In a 35-10 win over the San Francisco 49ers at home in Orchard Park, HC Sean McDermott's record coming out of the bye week ...

Quarterback Josh Allen and coach Sean McDermott deserve credit in overcoming lowered expectations in leading the Buffalo ...

Back-to-back blowout losses and another injury to star back Christian McCaffrey might just be the final blow to the dwindling ...

Buffalo Bills fans embraced the snowy conditions at Highmark Stadium in Orchard Park, New York, on December 1, as their team ...

The 49ers' playoff hopes are essentially dead now, and it became that way once McCaffrey went down with an unknown injury. On ...

The Buffalo Bills won the turnover battle for the 10th time in 12 games in their rout of the San Francisco 49ers on Sunday ...

There's even a chance Guerendo, who pulled his hamstring on the first day of training camp and missed the first two preseason ...

The weather outside was frightful at Highmark Stadium in Orchard Park, New York on Sunday night, but the way the San ...

Josh Allen of the Buffalo Bills and head coach Sean McDermott make snow angels while being interviewed after the Bills ...