The San Francisco 49ers looked out of their element as the Buffalo Bills cruised to an easy 35-10 win on Sunday Night ...

See what Kyle Shanahan, Brock Purdy, Sean McDermott and Josh Allen had to say following the Week 13 primetime contest.

San Francisco 49ers running back Christian McCaffrey suffered a knee injury and limped to the locker room in the second ...

Tom Brady is turning heads with his latest Instagram photo. The 47-year-old retired quarterback showed off his impressive physique in a post on Monday, Dec. 2, with a photo from a recent fishing ...

The 49ers just lost their second game in a row by at least 25 points for the first time since Jim Tomsula was the head coach.

The Buffalo Bills (10-2) came into Sunday’s game against the San Francisco 49ers (5-7) looking to clinch the AFC East for the ...

One last note of the bizarre: Niners tight end and eternal optimist George Kittle referenced a speech Shanahan gave back in ...

San Francisco 49ers head coach Kyle Shanahan revealed after Sunday night's loss to the Buffalo Bills that running back ...

San Francisco 49ers star running back Christian McCaffrey's season is in jeopardy after he sustained what is believed to be a ...

Bills quarterback Josh Allen's fiancée, Hailee Steinfeld, is spotted for the first time since the couple announcement their ...

Josh Allen is feeling "free" after popping the question to Hailee Steinfeld. After he and the Buffalo Bills put up a huge win ...

A frosty Alberta Clipper weatherfront could bring snow to City before the end of the week, though a cold rain is more likely.